A comparative study between propofol and thiopentone for hemodynamic parameters during induction of general anesthesia in surgical patients

Rakesh Kushwaha; Savita Choudhary

doi:10.5455/jmas.247007

2025, Vol: 15, Issue: 2

15 / 2Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

« Previous Article

Original Article
Online Published: 05 Jan 2017

J Med Allied Sci. 2017; 7(1): 9-13

doi: 10.5455/jmas.247007

A comparative study between propofol and thiopentone for hemodynamic parameters during induction of general anesthesia in surgical patients

Rakesh Kushwaha, Savita Choudhary.

Cited By: 1

Abstract
Hemodynamic stability is very much important during induction of general anesthesia. So, this study was planned to compare hemodynamic parameters during induction by thiopentone and propofol. This prospective study was conducted after approval from institutional ethics committee in non-hypertensive patients of ASA grade I and II aged between 18-60 yrs of either sex, admitted for different surgical procedure. The patients were randomized into group P (propofol) and group T (thiopentone). Heart rate, both systolic (SBP) and diastolic blood pressure (DBP) were recorded during induction and at 1 minutes, 2 minutes, 3 minutes and 4 minutes interval after intubation. Thirty patients in each group were included during study period. After induction, there was fall in both mean SBP and DBP after an increase during intubation which was more in group T (p˂0.05). The statistically significant difference was observed only at 1min between two groups for SBP (P value <0.05). The mean heart rate was almost similar at pre induction time in both the groups (p>0.05). There was rise in heart rate during intubation in both the groups, thereafter heart rate started decreasing. The fall was similar in both the group at any given point of observation (P value >0.05). Both propofol and thiopentone alter the blood pressure and heart rate during induction in surgical patients which are more pronounced in thiopentone but these changes return close to baseline value earlier in case of propofol. So, propofol could be the preferred inducing agent in hemodynamically unstable patients.

Key words: Hemodynamic parameters, Induction, Intubation, Propofol, Thiopentone

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Rakesh Kushwaha Articles by Savita Choudhary
	on Google
	on Google Scholar

This Article Cited By the following articles

COMPARISON OF THIOPENTONE (1.25%) AND PROPOFOL (1%) FOR INSERTION OF LARYNGEAL MASK AIRWAY IN PAEDIATRIC PATIENTS Journal of Evolution of Medical and Dental Sciences 2019; 8(3): 211.	1

How to Cite this Article

Pubmed Style

Kushwaha R, Choudhary S. A comparative study between propofol and thiopentone for hemodynamic parameters during induction of general anesthesia in surgical patients. J Med Allied Sci. 2017; 7(1): 9-13. doi:10.5455/jmas.247007

Web Style

Kushwaha R, Choudhary S. A comparative study between propofol and thiopentone for hemodynamic parameters during induction of general anesthesia in surgical patients. https://jmas.in/?mno=247007 [Access: June 26, 2026]. doi:10.5455/jmas.247007

AMA (American Medical Association) Style

Kushwaha R, Choudhary S. A comparative study between propofol and thiopentone for hemodynamic parameters during induction of general anesthesia in surgical patients. J Med Allied Sci. 2017; 7(1): 9-13. doi:10.5455/jmas.247007

Vancouver/ICMJE Style

Kushwaha R, Choudhary S. A comparative study between propofol and thiopentone for hemodynamic parameters during induction of general anesthesia in surgical patients. J Med Allied Sci. (2017), [cited June 26, 2026]; 7(1): 9-13. doi:10.5455/jmas.247007

Harvard Style

Kushwaha, R. & Choudhary, . S. (2017) A comparative study between propofol and thiopentone for hemodynamic parameters during induction of general anesthesia in surgical patients. J Med Allied Sci, 7 (1), 9-13. doi:10.5455/jmas.247007

Turabian Style

Kushwaha, Rakesh, and Savita Choudhary. 2017. A comparative study between propofol and thiopentone for hemodynamic parameters during induction of general anesthesia in surgical patients. Journal of Medical and Allied Sciences, 7 (1), 9-13. doi:10.5455/jmas.247007

Chicago Style

Kushwaha, Rakesh, and Savita Choudhary. "A comparative study between propofol and thiopentone for hemodynamic parameters during induction of general anesthesia in surgical patients." Journal of Medical and Allied Sciences 7 (2017), 9-13. doi:10.5455/jmas.247007

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Kushwaha, R. & Choudhary, . S. (2017) A comparative study between propofol and thiopentone for hemodynamic parameters during induction of general anesthesia in surgical patients. Journal of Medical and Allied Sciences, 7 (1), 9-13. doi:10.5455/jmas.247007

About Journal of Medical and Allied Sciences

Contact Information

How to cite this article


About Journal of Medical and Allied Sciences Welcome to the Journal of Medical and Allied Sciences (JMAS), an official international publication of Deccan College of Medical Sciences, for rapid publi ... Read more. For best results, please use Internet Explorer or Google Chrome.	Contact Information By regular mail/speed post/courier Dr. Kazi Mudabbir Ahmed Editor, JMAS, Deccan College of Medical Sciences, DMRL ‘X’ Road, Kanchanbagh (PO), Hyderabad-500 058, Telangana, India. By email: editorialoffice@jmas.in By phone: +91 40 24340225, 24340129 By Mobile: +91-8522828349 By fax: +91 40 24340235